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KMID : 0607519960040010037
Korean Journal of Psychosomatic Medicine
1996 Volume.4 No. 1 p.37 ~ p.43
Relationship between Changes in Manic Symptoms and in Thyroid Hormone Level
Shin Jong-Ho

Woo Kwang-Eun
Park Jin-Han
Abstract
This study was designed to investigate the relationship between changes in manic symptoms and in thyroid hormone level in manic patients. Thyroid hormones(T3, T4) and TSH were measured, and Young¡¯s Mania Rating Scale(YMRS) was scored in twenty manic inpatients, at the time of admission and 6 weeks later. Mean value of T3 was slightly increased(increase : 9, decrease : 11). Mean value of T4 was fairly decreased(increase 4, decrease 16), while that of TSH was increased(increase 14, decrease : 6). Mean total score of YMRS was fairly decreased and mean values of each eleven subscales were decreased. Subjects were classified as increased, decreased and unchanged group for each thyroid hormones. for T3, there was statistically significant differences in YMRS subscale of 6(speech : speed/amount), 7(language, thought disturbance) and 10(appereance) between 3 groups. With the above results, the changes of manic symptom during the course of illness could probably be indicated by the thyroid hormon change, and manic symptoms could be classified as subtypes in terms of thyroid hormone change.
KEYWORD
Manic symptom, Symptom change, Thyroid hormone
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